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Determination of STAT5 and GH Genes Polymorphisms and Their Influence on Productivity Traits of Beef Cattle Reared in Lithuania
Volume 82, Issue 1 (2024): Veterinarija ir Zootechnika, pp. 42–46
Nijolė Pečiulaitienė   Ramutė Mišeikienė   Kristina Morkūnienė     All authors (7)

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Pub. online: 30 November 2024      Type: Article      Open accessOpen Access

Received
20 May 2024
Revised
9 August 2024
Accepted
10 September 2024
Published
30 November 2024

Abstract

The aim of this study was to investigate the prevalence of polymorphisms of STAT5 and GH genes and to determine their influence on the productivity traits in beef cattle. A total of 95 animals were genotyped, belonging to the breeds Angus, Limousin, Galloway and Simmental. Polymorphisms of STAT5 and GH locus were identified using a PCR-RFLP method. The evaluation of the STAT5 gene polymorphism (7 exon, 6853C> T) demonstrated that C allele (frequency 0.959) and CC genotype (frequency 0.918) were the most common in beef bull populations reared in Lithuania. This polymorphism had a statistically significant effect on the live weight index of animals. The examination of the GH gene polymorphism (5 exon, 2141C> G) revealed that the G gene allele (frequency 0.612) and heterozygous CG genotype (frequency 0.424) were the most common. This polymorphism had a statistically significant effect on daily bull weight and live weight. Bulls of the homozygous CC genotype exhibited better economic characteristics. In conclusion, our results demonstrated the potential of polymorphisms of GH and STAT5 genes as candidates for the investigation of quantitative traits in cattle.

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Keywords
cattle GH gene STAT5 gene PCR-RFLP

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